ENSG00000130699


Homo sapiens

Features
Gene ID: ENSG00000130699
  
Biological name :TAF4
  
Synonyms : O00268 / TAF4 / TATA-box binding protein associated factor 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 61953469
Gene end: 62065810
  
Corresponding Affymetrix probe sets: 208545_x_at (Human Genome U133 Plus 2.0 Array)   213090_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000252996
Ensembl peptide - ENSP00000476270
Ensembl peptide - ENSP00000476294
NCBI entrez gene - 6874     See in Manteia.
OMIM - 601796
RefSeq - NM_003185
RefSeq Peptide - NP_003176
swissprot - O00268
swissprot - V9GY03
swissprot - V9GY14
Ensembl - ENSG00000130699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 taf4aENSDARG00000068192Danio rerio
 TAF4ENSGALG00000005121Gallus gallus
 Taf4ENSMUSG00000039117Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TAF4B / Q92750 / TATA-box binding protein associated factor 4bENSG0000014138428


Protein motifs (from Interpro)
Interpro ID Name
 IPR003894  TAFH/NHR1
 IPR007900  Transcription initiation factor TFIID component TAF4
 IPR009072  Histone-fold
 IPR037249  TAFH/NHR1 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006352 DNA-templated transcription, initiation IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006367 transcription initiation from RNA polymerase II promoter TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005669 transcription factor TFIID complex IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0032991 protein-containing complex IMP
 cellular_componentGO:0033276 transcription factor TFTC complex IDA
 cellular_componentGO:0071339 MLL1 complex IDA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003713 transcription coactivator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017162 aryl hydrocarbon receptor binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
RNA Polymerase II Pre-transcription Events
Regulation of TP53 Activity through Phosphorylation
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Initiation And Promoter Clearance


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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