ENSG00000130755


Homo sapiens

Features
Gene ID: ENSG00000130755
  
Biological name :GMFG
  
Synonyms : glia maturation factor gamma / GMFG / O60234
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 39328353
Gene end: 39342372
  
Corresponding Affymetrix probe sets: 204220_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000469485
Ensembl peptide - ENSP00000469755
Ensembl peptide - ENSP00000469813
Ensembl peptide - ENSP00000469877
Ensembl peptide - ENSP00000471139
Ensembl peptide - ENSP00000471786
Ensembl peptide - ENSP00000472249
Ensembl peptide - ENSP00000472707
Ensembl peptide - ENSP00000253054
Ensembl peptide - ENSP00000468894
Ensembl peptide - ENSP00000469050
NCBI entrez gene - 9535     See in Manteia.
OMIM - 604104
RefSeq - NM_001301008
RefSeq - NM_004877
RefSeq Peptide - NP_001287937
RefSeq Peptide - NP_004868
swissprot - O60234
swissprot - M0QX47
swissprot - M0QXC2
swissprot - M0QXZ6
swissprot - M0QYD5
swissprot - M0QYG8
swissprot - M0QYJ8
swissprot - M0R0C1
swissprot - M0R1D2
swissprot - M0R2P2
Ensembl - ENSG00000130755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GmfgENSMUSG00000060791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GMFB / P60983 / glia maturation factor betaENSG0000019704581


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR011171  Glia maturation factor
 IPR029006  ADF-H/Gelsolin-like domain superfamily
 IPR030076  Glia maturation factor gamma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0071846 actin filament debranching IEA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity TAS
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0071933 Arp2/3 complex binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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