ENSG00000197045


Homo sapiens

Features
Gene ID: ENSG00000197045
  
Biological name :GMFB
  
Synonyms : glia maturation factor beta / GMFB / P60983
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q22.2
Gene start: 54474484
Gene end: 54489196
  
Corresponding Affymetrix probe sets: 202543_s_at (Human Genome U133 Plus 2.0 Array)   202544_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479543
Ensembl peptide - ENSP00000487065
Ensembl peptide - ENSP00000350757
Ensembl peptide - ENSP00000451473
Ensembl peptide - ENSP00000451920
Ensembl peptide - ENSP00000452410
NCBI entrez gene - 2764     See in Manteia.
OMIM - 601713
RefSeq - NM_004124
RefSeq Peptide - NP_004115
swissprot - G3V3X4
swissprot - G3V4P8
swissprot - P60983
Ensembl - ENSG00000197045
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmfbENSDARG00000028327Danio rerio
 GMFBENSGALG00000012208Gallus gallus
 GmfbENSMUSG00000062014Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GMFG / O60234 / glia maturation factor gammaENSG0000013075581


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR011171  Glia maturation factor
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007612 learning IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity TAS
 molecular_functionGO:0004871 obsolete signal transducer activity TAS
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0071933 Arp2/3 complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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