ENSMUSG00000062014


Mus musculus

Features
Gene ID: ENSMUSG00000062014
  
Biological name :Gmfb
  
Synonyms : glia maturation factor, beta / Gmfb / Q9CQI3
  
Possible biological names infered from orthology : P60983
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C1
Gene start: 46808149
Gene end: 46822242
  
Corresponding Affymetrix probe sets: 10419274 (MoGene1.0st)   1417069_a_at (Mouse Genome 430 2.0 Array)   1431686_a_at (Mouse Genome 430 2.0 Array)   1431687_at (Mouse Genome 430 2.0 Array)   1448570_at (Mouse Genome 430 2.0 Array)   1448571_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000154491
Ensembl peptide - ENSMUSP00000078293
Ensembl peptide - ENSMUSP00000107448
Ensembl peptide - ENSMUSP00000153896
NCBI entrez gene - 63985     See in Manteia.
MGI - MGI:1927133
RefSeq - NM_022023
RefSeq Peptide - NP_071306
swissprot - Q9CQI3
Ensembl - ENSMUSG00000062014
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gmfbENSDARG00000028327Danio rerio
 GMFBENSGALG00000012208Gallus gallus
 GMFBENSG00000197045Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gmfg / Q9ERL7 / glia maturation factor, gamma / O60234*ENSMUSG0000006079179


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR011171  Glia maturation factor
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007612 learning IMP
 biological_processGO:0007626 locomotory behavior IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0071933 Arp2/3 complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000847 abnormal metencephalon morphology "any malformation or absence of the anterior part of the rhombencephalon" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Igbp1tm1Cbt/Igbp1+,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
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Allelic Composition: Igbp1tm1Cbt/Igbp1+,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0002807 abnormal eye blink conditioning behavior "defects in the ability of an animal to learn to blink in anticipation of an aversive stimulus (e.g., an airpuff to the eyelid) following repeated pairings with a neutral stimulus (e.g., a tone); such learning is only adaptive if the animal is able to learn the precise timing between the conditioned and unconditioned stimuli " [CFG:Center for Functional Genomics , Northwestern University]
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Allelic Composition: Igbp1tm1Cbt/Igbp1+,Tg(Lck-cre)1Cwi/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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