ENSG00000130811


Homo sapiens

Features
Gene ID: ENSG00000130811
  
Biological name :EIF3G
  
Synonyms : EIF3G / eukaryotic translation initiation factor 3 subunit G / O75821
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.2
Gene start: 10115017
Gene end: 10119918
  
Corresponding Affymetrix probe sets: 208887_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465882
Ensembl peptide - ENSP00000465933
Ensembl peptide - ENSP00000466860
Ensembl peptide - ENSP00000466943
Ensembl peptide - ENSP00000467187
Ensembl peptide - ENSP00000468159
Ensembl peptide - ENSP00000468313
Ensembl peptide - ENSP00000253108
NCBI entrez gene - 8666     See in Manteia.
OMIM - 603913
RefSeq - NM_003755
RefSeq Peptide - NP_003746
swissprot - O75821
swissprot - K7EL20
swissprot - K7EL60
swissprot - K7ENA8
swissprot - K7ENH0
swissprot - K7EP16
swissprot - K7ER90
swissprot - K7ERL8
Ensembl - ENSG00000130811
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif3gENSDARG00000016889Danio rerio
 Eif3gENSMUSG00000070319Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR017334  Eukaryotic translation initiation factor 3 subunit G
 IPR024675  Eukaryotic translation initiation factor 3 subunit G, N-terminal
 IPR034240  eIF3G, RNA recognition motif
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0075525 viral translational termination-reinitiation IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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