ENSG00000131203


Homo sapiens

Features
Gene ID: ENSG00000131203
  
Biological name :IDO1
  
Synonyms : IDO1 / indoleamine 2,3-dioxygenase 1 / P14902
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p11.21
Gene start: 39902275
Gene end: 39928444
  
Corresponding Affymetrix probe sets: 210029_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430505
Ensembl peptide - ENSP00000428716
Ensembl peptide - ENSP00000430950
Ensembl peptide - ENSP00000429297
Ensembl peptide - ENSP00000429933
Ensembl peptide - ENSP00000253513
NCBI entrez gene - 3620     See in Manteia.
OMIM - 147435
RefSeq - NM_002164
RefSeq Peptide - NP_002155
swissprot - A0A140T9Z2
swissprot - E5RIX2
swissprot - P14902
swissprot - J3KN03
swissprot - E5RH36
Ensembl - ENSG00000131203
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ido1ENSMUSG00000031551Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IDO2 / Q6ZQW0 / indoleamine 2,3-dioxygenase 2ENSG0000018867643


Protein motifs (from Interpro)
Interpro ID Name
 IPR000898  Indoleamine 2,3-dioxygenase
 IPR037217  Tryptophan/Indoleamine 2,3-dioxygenase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002534 cytokine production involved in inflammatory response IEA
 biological_processGO:0002666 positive regulation of T cell tolerance induction IEA
 biological_processGO:0002678 positive regulation of chronic inflammatory response IEA
 biological_processGO:0002830 positive regulation of type 2 immune response IEA
 biological_processGO:0006569 tryptophan catabolic process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007565 female pregnancy TAS
 biological_processGO:0019441 tryptophan catabolic process to kynurenine IEA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032693 negative regulation of interleukin-10 production IEA
 biological_processGO:0032735 positive regulation of interleukin-12 production IEA
 biological_processGO:0033555 multicellular organismal response to stress IEA
 biological_processGO:0034276 kynurenic acid biosynthetic process IEA
 biological_processGO:0036269 swimming behavior IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070233 negative regulation of T cell apoptotic process IEA
 biological_processGO:0070234 positive regulation of T cell apoptotic process IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0030485 smooth muscle contractile fiber IEA
 cellular_componentGO:0032421 stereocilium bundle IEA
 molecular_functionGO:0004833 tryptophan 2,3-dioxygenase activity EXP
 molecular_functionGO:0009055 electron transfer activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0033754 indoleamine 2,3-dioxygenase activity IMP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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