ENSG00000131374


Homo sapiens

Features
Gene ID: ENSG00000131374
  
Biological name :TBC1D5
  
Synonyms : Q92609 / TBC1D5 / TBC1 domain family member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p24.3
Gene start: 17157162
Gene end: 18444817
  
Corresponding Affymetrix probe sets: 201813_s_at (Human Genome U133 Plus 2.0 Array)   201814_at (Human Genome U133 Plus 2.0 Array)   201815_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398127
Ensembl peptide - ENSP00000396850
Ensembl peptide - ENSP00000399967
Ensembl peptide - ENSP00000424998
Ensembl peptide - ENSP00000415379
Ensembl peptide - ENSP00000414250
Ensembl peptide - ENSP00000414159
Ensembl peptide - ENSP00000411925
Ensembl peptide - ENSP00000411780
Ensembl peptide - ENSP00000410596
Ensembl peptide - ENSP00000408603
Ensembl peptide - ENSP00000405886
Ensembl peptide - ENSP00000402935
Ensembl peptide - ENSP00000253692
Ensembl peptide - ENSP00000387395
Ensembl peptide - ENSP00000393882
Ensembl peptide - ENSP00000396239
NCBI entrez gene - 9779     See in Manteia.
OMIM - 615740
RefSeq - XM_017007568
RefSeq - XM_005265615
RefSeq - XM_005265616
RefSeq - XM_006713430
RefSeq - XM_011534281
RefSeq - XM_011534283
RefSeq - XM_011534284
RefSeq - XM_011534286
RefSeq - XM_011534287
RefSeq - XM_017007552
RefSeq - XM_017007553
RefSeq - XM_017007554
RefSeq - XM_017007555
RefSeq - XM_017007556
RefSeq - XM_017007557
RefSeq - XM_017007558
RefSeq - XM_017007559
RefSeq - XM_017007560
RefSeq - XM_017007561
RefSeq - XM_017007562
RefSeq - XM_017007563
RefSeq - XM_017007564
RefSeq - XM_017007565
RefSeq - XM_017007566
RefSeq - XM_017007567
RefSeq - NM_001134381
RefSeq - NM_014744
RefSeq - XM_005265611
RefSeq - XM_005265612
RefSeq - XM_005265614
RefSeq Peptide - NP_001127853
RefSeq Peptide - NP_001336002
RefSeq Peptide - NP_001336003
RefSeq Peptide - NP_001336004
RefSeq Peptide - NP_001336005
RefSeq Peptide - NP_001336006
RefSeq Peptide - NP_001336007
RefSeq Peptide - NP_001336008
RefSeq Peptide - NP_001336009
RefSeq Peptide - NP_055559
swissprot - F2Z3C3
swissprot - F2Z3I5
swissprot - C9K0P2
swissprot - B9A6K1
swissprot - Q92609
swissprot - C9JWX0
swissprot - C9JW04
swissprot - C9JNM0
swissprot - C9JMP7
swissprot - C9JIU4
swissprot - C9JED7
swissprot - C9JDR8
swissprot - C9J3F6
swissprot - C9J397
Ensembl - ENSG00000131374
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d5ENSDARG00000036212Danio rerio
 TBC1D5ENSGALG00000011251Gallus gallus
 Q80XQ2ENSMUSG00000023923Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NVG8 / TBC1D13 / TBC1 domain family member 13ENSG0000010702112


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002092 positive regulation of receptor internalization IMP
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006914 autophagy IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy IMP
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0042594 response to starvation IDA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030122 AP-2 adaptor complex IDA
 cellular_componentGO:0030904 retromer complex IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:1990316 Atg1/ULK1 kinase complex IDA
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IBA
 molecular_functionGO:0035612 AP-2 adaptor complex binding IDA
 molecular_functionGO:1905394 retromer complex binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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