ENSG00000131459


Homo sapiens

Features
Gene ID: ENSG00000131459
  
Biological name :GFPT2
  
Synonyms : GFPT2 / glutamine-fructose-6-phosphate transaminase 2 / O94808
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.3
Gene start: 180300690
Gene end: 180353387
  
Corresponding Affymetrix probe sets: 205100_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000253778
Ensembl peptide - ENSP00000431125
Ensembl peptide - ENSP00000422771
NCBI entrez gene - 9945     See in Manteia.
OMIM - 603865
RefSeq - NM_005110
RefSeq - XM_017010100
RefSeq - XM_006714942
RefSeq Peptide - NP_005101
swissprot - E5RJP4
swissprot - O94808
swissprot - A0A0S2Z4X9
swissprot - D6RAC1
Ensembl - ENSG00000131459
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gfpt2ENSDARG00000044094Danio rerio
 GFPT2ENSGALG00000039705Gallus gallus
 Gfpt2ENSMUSG00000020363Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GFPT1 / Q06210 / glutamine--fructose-6-phosphate transaminase 1ENSG0000019838079


Protein motifs (from Interpro)
Interpro ID Name
 IPR001347  Sugar isomerase (SIS)
 IPR005855  Glucosamine-fructose-6-phosphate aminotransferase, isomerising
 IPR017932  Glutamine amidotransferase type 2 domain
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR035466  GlmS/AgaS, SIS domain 1
 IPR035490  GlmS/FrlB, SIS domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process TAS
 biological_processGO:0006047 UDP-N-acetylglucosamine metabolic process IBA
 biological_processGO:0006048 UDP-N-acetylglucosamine biosynthetic process TAS
 biological_processGO:0006112 energy reserve metabolic process TAS
 biological_processGO:0006487 protein N-linked glycosylation IBA
 biological_processGO:0006541 glutamine metabolic process IEA
 biological_processGO:1901135 carbohydrate derivative metabolic process IEA
 biological_processGO:1901137 carbohydrate derivative biosynthetic process IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0097367 carbohydrate derivative binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of UDP-N-acetyl-glucosamine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr