ENSMUSG00000020363


Mus musculus

Features
Gene ID: ENSMUSG00000020363
  
Biological name :Gfpt2
  
Synonyms : Gfpt2 / Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 / Q9Z2Z9
  
Possible biological names infered from orthology : glutamine-fructose-6-phosphate transaminase 2 / O94808
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B1.2
Gene start: 49794178
Gene end: 49838613
  
Corresponding Affymetrix probe sets: 10375614 (MoGene1.0st)   1418753_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020629
NCBI entrez gene - 14584     See in Manteia.
MGI - MGI:1338883
RefSeq - NM_013529
RefSeq Peptide - NP_038557
swissprot - Q9Z2Z9
Ensembl - ENSMUSG00000020363
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gfpt2ENSDARG00000044094Danio rerio
 GFPT2ENSGALG00000039705Gallus gallus
 GFPT2ENSG00000131459Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gfpt1 / P47856 / Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 / Q06210* / glutamine--fructose-6-phosphate transaminase 1*ENSMUSG0000002999279


Protein motifs (from Interpro)
Interpro ID Name
 IPR001347  Sugar isomerase (SIS)
 IPR005855  Glucosamine-fructose-6-phosphate aminotransferase, isomerising
 IPR017932  Glutamine amidotransferase type 2 domain
 IPR029055  Nucleophile aminohydrolases, N-terminal
 IPR035466  GlmS/AgaS, SIS domain 1
 IPR035490  GlmS/FrlB, SIS domain 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006002 fructose 6-phosphate metabolic process IBA
 biological_processGO:0006047 UDP-N-acetylglucosamine metabolic process IBA
 biological_processGO:0006048 UDP-N-acetylglucosamine biosynthetic process IEA
 biological_processGO:0006487 protein N-linked glycosylation IBA
 biological_processGO:0006541 glutamine metabolic process TAS
 biological_processGO:1901135 carbohydrate derivative metabolic process IEA
 biological_processGO:1901137 carbohydrate derivative biosynthetic process IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEP
 molecular_functionGO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity TAS
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0097367 carbohydrate derivative binding IEA


Pathways (from Reactome)
Pathway description
Synthesis of UDP-N-acetyl-glucosamine


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

 MP:0002100 abnormal tooth morphology "atypical size, shape or hard tissue structure of the teeth " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

 MP:0011968 decreased threshold for auditory brainstem response "reduction in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system" [MGI:csmith]
Show

Allelic Composition: Gbx1tm1b(KOMP)Wtsi/Gbx1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Gbx1tm1b(KOMP)Wtsi/H

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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