ENSG00000131620


Homo sapiens

Features
Gene ID: ENSG00000131620
  
Biological name :ANO1
  
Synonyms : ANO1 / anoctamin 1 / Q5XXA6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.3
Gene start: 70078302
Gene end: 70189528
  
Corresponding Affymetrix probe sets: 1555269_a_at (Human Genome U133 Plus 2.0 Array)   218804_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433445
Ensembl peptide - ENSP00000432843
Ensembl peptide - ENSP00000435797
Ensembl peptide - ENSP00000436392
Ensembl peptide - ENSP00000435868
Ensembl peptide - ENSP00000319477
Ensembl peptide - ENSP00000347454
NCBI entrez gene - 55107     See in Manteia.
OMIM - 610108
RefSeq - XM_017017957
RefSeq - XM_011545126
RefSeq - XM_011545127
RefSeq - XM_011545128
RefSeq - XM_011545129
RefSeq - XM_011545131
RefSeq - XM_017017956
RefSeq - NM_018043
RefSeq - XM_006718602
RefSeq - XM_006718604
RefSeq - XM_006718605
RefSeq - XM_011545121
RefSeq - XM_011545123
RefSeq - XM_011545124
RefSeq - XM_011545125
RefSeq Peptide - NP_060513
swissprot - E9PS90
swissprot - E9PP68
swissprot - H0YDD9
swissprot - E9PNA7
swissprot - Q5XXA6
Ensembl - ENSG00000131620
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ano1ENSDARG00000102335Danio rerio
 ANO1ENSGALG00000041808Gallus gallus
 Ano1ENSMUSG00000031075Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANO2 / Q9NQ90 / anoctamin 2ENSG0000004761758
ANO4 / Q32M45 / anoctamin 4ENSG0000015157238
ANO3 / Q9BYT9 / anoctamin 3ENSG0000013434337
ANO5 / Q75V66 / anoctamin 5ENSG0000017171435
ANO6 / Q4KMQ2 / anoctamin 6ENSG0000017711933
ANO7 / Q6IWH7 / anoctamin 7ENSG0000014620533
ANO9 / A1A5B4 / anoctamin 9ENSG0000018510125
ANO8 / Q9HCE9 / anoctamin 8ENSG0000007485517
ANO10 / Q9NW15 / anoctamin 10ENSG0000016074615


Protein motifs (from Interpro)
Interpro ID Name
 IPR007632  Anoctamin
 IPR031287  Anoctamin-1
 IPR032394  Anoctamin, dimerisation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IDA
 biological_processGO:0006821 chloride transport ISS
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0015705 iodide transport IMP
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0034605 cellular response to heat IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain ISS
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005227 calcium activated cation channel activity IDA
 molecular_functionGO:0005229 intracellular calcium activated chloride channel activity TAS
 molecular_functionGO:0005247 voltage-gated chloride channel activity ISS
 molecular_functionGO:0005254 chloride channel activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015111 iodide transmembrane transporter activity IMP
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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