ENSG00000131771


Homo sapiens

Features
Gene ID: ENSG00000131771
  
Biological name :PPP1R1B
  
Synonyms : PPP1R1B / protein phosphatase 1 regulatory inhibitor subunit 1B / Q9UD71
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 39626740
Gene end: 39636626
  
Corresponding Affymetrix probe sets: 225165_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462137
Ensembl peptide - ENSP00000377810
Ensembl peptide - ENSP00000462522
Ensembl peptide - ENSP00000462841
Ensembl peptide - ENSP00000254079
Ensembl peptide - ENSP00000377808
NCBI entrez gene - 84152     See in Manteia.
OMIM - 604399
RefSeq - XM_017025217
RefSeq - NM_001242464
RefSeq - NM_032192
RefSeq - NM_181505
RefSeq - XM_017025216
RefSeq Peptide - NP_115568
RefSeq Peptide - NP_001229393
RefSeq Peptide - NP_852606
swissprot - J3KSJ8
swissprot - J3KT77
swissprot - B3KVQ9
swissprot - A0A024R1R3
swissprot - Q9UD71
Ensembl - ENSG00000131771
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp1r1bENSDARG00000076280Danio rerio
 PPP1R1BENSGALG00000044406Gallus gallus
 Q60829ENSMUSG00000061718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008466  Protein phosphatase inhibitor 1
 IPR015670  Protein phosphatase 1 regulatory subunit 1B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001975 response to amphetamine IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007621 negative regulation of female receptivity IEA
 biological_processGO:0007626 locomotory behavior IEA
 biological_processGO:0008542 visual learning IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IDA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0043987 histone H3-S10 phosphorylation IEA
 biological_processGO:0048148 behavioral response to cocaine IEA
 biological_processGO:0071901 negative regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity TAS
 molecular_functionGO:0004862 cAMP-dependent protein kinase inhibitor activity TAS
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IDA
 molecular_functionGO:0004865 protein serine/threonine phosphatase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity TAS
 molecular_functionGO:0031748 D1 dopamine receptor binding IEA
 molecular_functionGO:0031749 D2 dopamine receptor binding IEA
 molecular_functionGO:0031750 D3 dopamine receptor binding IEA
 molecular_functionGO:0031751 D4 dopamine receptor binding IEA
 molecular_functionGO:0031752 D5 dopamine receptor binding IEA


Pathways (from Reactome)
Pathway description
DARPP-32 events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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