ENSG00000132471


Homo sapiens

Features
Gene ID: ENSG00000132471
  
Biological name :WBP2
  
Synonyms : Q969T9 / WBP2 / WW domain binding protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 75845699
Gene end: 75856507
  
Corresponding Affymetrix probe sets: 209117_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467579
Ensembl peptide - ENSP00000486675
Ensembl peptide - ENSP00000468793
Ensembl peptide - ENSP00000467583
Ensembl peptide - ENSP00000254806
Ensembl peptide - ENSP00000415251
Ensembl peptide - ENSP00000464768
Ensembl peptide - ENSP00000464782
Ensembl peptide - ENSP00000464820
Ensembl peptide - ENSP00000465052
Ensembl peptide - ENSP00000466450
Ensembl peptide - ENSP00000466999
NCBI entrez gene - 23558     See in Manteia.
OMIM - 606962
RefSeq - NM_012478
RefSeq - XM_011524580
RefSeq - NM_001348170
RefSeq Peptide - NP_001335099
RefSeq Peptide - NP_001317428
RefSeq Peptide - NP_036610
swissprot - A6NG10
swissprot - K7ESN4
swissprot - Q969T9
swissprot - K7ENL2
swissprot - A0A024R8L1
swissprot - K7EIJ0
swissprot - K7EIK1
swissprot - K7EIN1
swissprot - K7EJ75
swissprot - K7EMC9
Ensembl - ENSG00000132471
  
Related genetic diseases (OMIM): 617639 - Deafness, autosomal recessive 107, 617639
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wbp2ENSDARG00000056605Danio rerio
 WBP2ENSGALG00000002219Gallus gallus
 Wbp2ENSMUSG00000034341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6ICG8 / WBP2NL / WBP2 N-terminal likeENSG0000018306633


Protein motifs (from Interpro)
Interpro ID Name
 IPR004182  GRAM domain
 IPR011993  PH-like domain superfamily
 IPR033598  WW domain-binding protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0032570 response to progesterone IDA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IDA
 biological_processGO:0043627 response to estrogen IDA
 biological_processGO:0045184 establishment of protein localization IMP
 biological_processGO:0045815 positive regulation of gene expression, epigenetic IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050847 progesterone receptor signaling pathway IDA
 biological_processGO:0071391 cellular response to estrogen stimulus IEA
 biological_processGO:0071442 positive regulation of histone H3-K14 acetylation IMP
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IMP
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030331 estrogen receptor binding IPI
 molecular_functionGO:0031490 chromatin DNA binding IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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