ENSG00000132744


Homo sapiens

Features
Gene ID: ENSG00000132744
  
Biological name :ACY3
  
Synonyms : ACY3 / aminoacylase 3 / Q96HD9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.2
Gene start: 67642555
Gene end: 67650659
  
Corresponding Affymetrix probe sets: 1554974_at (Human Genome U133 Plus 2.0 Array)   230481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000255082
Ensembl peptide - ENSP00000434270
NCBI entrez gene - 91703     See in Manteia.
OMIM - 614413
RefSeq - XM_017018551
RefSeq - NM_080658
RefSeq - XM_017018549
RefSeq - XM_017018550
RefSeq Peptide - NP_542389
swissprot - Q96HD9
swissprot - E9PRA7
swissprot - A0A024R5L2
Ensembl - ENSG00000132744
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acy3.1ENSDARG00000093003Danio rerio
 acy3.2ENSDARG00000005525Danio rerio
 Acy3ENSMUSG00000024866Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASPA / P45381 / aspartoacylaseENSG0000010838143


Protein motifs (from Interpro)
Interpro ID Name
 IPR007036  Succinylglutamate desuccinylase/aspartoacylase
 IPR016708  Aspartoacylase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016032 viral process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0004046 aminoacylase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IEA
 molecular_functionGO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Aflatoxin activation and detoxification


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132744 ACY3 / Q96HD9 / aminoacylase 3  / complex






 

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