ENSG00000134321


Homo sapiens

Features
Gene ID: ENSG00000134321
  
Biological name :RSAD2
  
Synonyms : Q8WXG1 / radical S-adenosyl methionine domain containing 2 / RSAD2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p25.2
Gene start: 6865806
Gene end: 6898239
  
Corresponding Affymetrix probe sets: 213797_at (Human Genome U133 Plus 2.0 Array)   242625_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406427
Ensembl peptide - ENSP00000371471
NCBI entrez gene - 91543     See in Manteia.
OMIM - 607810
RefSeq - XM_011510415
RefSeq - NM_080657
RefSeq - XM_011510414
RefSeq Peptide - NP_542388
swissprot - Q8WXG1
swissprot - C9J674
Ensembl - ENSG00000134321
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rsad2ENSDARG00000004952Danio rerio
 RSAD2ENSGALG00000016400Gallus gallus
 Rsad2ENSMUSG00000020641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006638  Elp3/MiaB/NifB
 IPR007197  Radical SAM
 IPR013785  Aldolase-type TIM barrel
 IPR026372  Antiviral radical SAM protein viperin
 IPR034395  SPASM/twitch domain-containing


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009615 response to virus IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0034157 positive regulation of toll-like receptor 7 signaling pathway IEA
 biological_processGO:0034165 positive regulation of toll-like receptor 9 signaling pathway IEA
 biological_processGO:0035710 CD4-positive, alpha-beta T cell activation IEA
 biological_processGO:0043367 CD4-positive, alpha-beta T cell differentiation IEA
 biological_processGO:0045071 negative regulation of viral genome replication IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0051607 defense response to virus IDA
 biological_processGO:0060337 type I interferon signaling pathway TAS
 biological_processGO:2000553 positive regulation of T-helper 2 cell cytokine production IEA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005811 lipid droplet ISS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043621 protein self-association IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051539 4 iron, 4 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Interferon alpha/beta signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr