ENSG00000134809


Homo sapiens

Features
Gene ID: ENSG00000134809
  
Biological name :TIMM10
  
Synonyms : P62072 / TIMM10 / translocase of inner mitochondrial membrane 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.1
Gene start: 57528463
Gene end: 57530803
  
Corresponding Affymetrix probe sets: 1555764_s_at (Human Genome U133 Plus 2.0 Array)   218408_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433627
Ensembl peptide - ENSP00000435678
Ensembl peptide - ENSP00000257245
NCBI entrez gene - 26519     See in Manteia.
OMIM - 602251
RefSeq - NM_012456
RefSeq Peptide - NP_036588
swissprot - P62072
Ensembl - ENSG00000134809
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DI06ENSDARG00000069116Danio rerio
 TIMM10ENSGALG00000004845Gallus gallus
 P62073ENSMUSG00000027076Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004217  Tim10-like
 IPR027100  Mitochondrial import inner membrane translocase subunit Tim10
 IPR035427  Tim10-like domain superfamily
 IPR037376  Mitochondrial import inner membrane translocase subunit Tim10/12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0007605 sensory perception of sound TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0045039 protein import into mitochondrial inner membrane ISS
 biological_processGO:0072321 chaperone-mediated protein transport IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IDA
 cellular_componentGO:0005744 mitochondrial inner membrane presequence translocase complex TAS
 cellular_componentGO:0005758 mitochondrial intermembrane space TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042719 mitochondrial intermembrane space protein transporter complex IDA
 cellular_componentGO:0042721 mitochondrial inner membrane protein insertion complex IEA
 molecular_functionGO:0005215 transporter activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051087 chaperone binding IPI


Pathways (from Reactome)
Pathway description
Mitochondrial protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100575 TIMM9 / Q9Y5J7 / translocase of inner mitochondrial membrane 9  / complex
 ENSG00000132286 Q9Y5J6 / TIMM10B / translocase of inner mitochondrial membrane 10B  / complex / reaction
 ENSG00000177370 Q9Y584 / TIMM22 / translocase of inner mitochondrial membrane 22  / complex / reaction
 ENSG00000169100 P12236 / SLC25A6 / solute carrier family 25 member 6  / complex / reaction






 

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