ENSG00000169100


Homo sapiens

Features
Gene ID: ENSG00000169100
  
Biological name :SLC25A6
  
Synonyms : P12236 / SLC25A6 / solute carrier family 25 member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p22.33
Gene start: 1386152
Gene end: 1392724
  
Corresponding Affymetrix probe sets: 212085_at (Human Genome U133 Plus 2.0 Array)   212826_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370808
NCBI entrez gene - 293     See in Manteia.
OMIM - 300151
OMIM - 403000
RefSeq - NM_001636
RefSeq Peptide - NP_001627
swissprot - P12236
swissprot - Q6I9V5
Ensembl - ENSG00000169100
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC25A6ENSGALG00000016691Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P05141 / SLC25A5 / solute carrier family 25 member 5ENSG0000000502292
P12235 / SLC25A4 / solute carrier family 25 member 4ENSG0000015172988
Q9H0C2 / SLC25A31 / solute carrier family 25 member 31ENSG0000015147570


Protein motifs (from Interpro)
Interpro ID Name
 IPR002067  Mitochondrial carrier protein
 IPR002113  Adenine nucleotide translocator 1
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006626 protein targeting to mitochondrion TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0015853 adenine transport IEA
 biological_processGO:0015866 ADP transport IEA
 biological_processGO:0015867 ATP transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0046732 active induction of host immune response by virus TAS
 biological_processGO:0046902 regulation of mitochondrial membrane permeability IBA
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005744 mitochondrial inner membrane presequence translocase complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005471 ATP:ADP antiporter activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015207 adenine transmembrane transporter activity TAS
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial protein import
Influenza Virus Induced Apoptosis
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100575 TIMM9 / Q9Y5J7 / translocase of inner mitochondrial membrane 9  / complex / reaction
 ENSG00000134809 P62072 / TIMM10 / translocase of inner mitochondrial membrane 10  / complex / reaction
 ENSG00000169100 P12236 / SLC25A6 / solute carrier family 25 member 6  / complex
 ENSG00000177370 Q9Y584 / TIMM22 / translocase of inner mitochondrial membrane 22  / complex / reaction
 ENSG00000132286 Q9Y5J6 / TIMM10B / translocase of inner mitochondrial membrane 10B  / reaction / complex






 

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