ENSG00000005022


Homo sapiens

Features
Gene ID: ENSG00000005022
  
Biological name :SLC25A5
  
Synonyms : P05141 / SLC25A5 / solute carrier family 25 member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q24
Gene start: 119468400
Gene end: 119471319
  
Corresponding Affymetrix probe sets: 200657_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360671
NCBI entrez gene - 292     See in Manteia.
OMIM - 300150
RefSeq - NM_001152
RefSeq Peptide - NP_001143
swissprot - P05141
Ensembl - ENSG00000005022
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-251i10.1ENSDARG00000042521Danio rerio
 slc25a5ENSDARG00000092553Danio rerio
 SLC25A5ENSGALG00000008675Gallus gallus
 P51881ENSMUSG00000016319Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P12236 / SLC25A6 / solute carrier family 25 member 6ENSG0000016910092
P12235 / SLC25A4 / solute carrier family 25 member 4ENSG0000015172989
Q9H0C2 / SLC25A31 / solute carrier family 25 member 31ENSG0000015147570


Protein motifs (from Interpro)
Interpro ID Name
 IPR002067  Mitochondrial carrier protein
 IPR002113  Adenine nucleotide translocator 1
 IPR018108  Mitochondrial substrate/solute carrier
 IPR023395  Mitochondrial carrier domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0015853 adenine transport IEA
 biological_processGO:0015866 ADP transport IEA
 biological_processGO:0015867 ATP transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0050796 regulation of insulin secretion TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IMP
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IDA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071817 MMXD complex IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005471 ATP:ADP antiporter activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015207 adenine transmembrane transporter activity TAS
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000005022 P05141 / SLC25A5 / solute carrier family 25 member 5  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr