ENSG00000135018


Homo sapiens

Features
Gene ID: ENSG00000135018
  
Biological name :UBQLN1
  
Synonyms : Q9UMX0 / ubiquilin 1 / UBQLN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q21.32
Gene start: 83659963
Gene end: 83708203
  
Corresponding Affymetrix probe sets: 222989_s_at (Human Genome U133 Plus 2.0 Array)   222990_at (Human Genome U133 Plus 2.0 Array)   222991_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436912
Ensembl peptide - ENSP00000257468
Ensembl peptide - ENSP00000365576
Ensembl peptide - ENSP00000434194
NCBI entrez gene - 29979     See in Manteia.
OMIM - 605046
RefSeq - XM_005251948
RefSeq - NM_013438
RefSeq - NM_053067
RefSeq Peptide - NP_038466
RefSeq Peptide - NP_444295
swissprot - Q9UMX0
swissprot - A0A024R258
swissprot - H0YDS0
swissprot - H0YEZ9
Ensembl - ENSG00000135018
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000012585Gallus gallus
 Q8R317ENSMUSG00000005312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UHD9 / UBQLN2 / ubiquilin 2ENSG0000018802180
Q9NRR5 / UBQLN4 / ubiquilin 4ENSG0000016080363
Q9H347 / UBQLN3 / ubiquilin 3ENSG0000017552047
Q8IYU4 / UBQLNL / ubiquilin likeENSG0000017551828


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR006636  Heat shock chaperonin-binding
 IPR009060  UBA-like superfamily
 IPR015496  Ubiquilin
 IPR015940  Ubiquitin-associated domain
 IPR028799  Ubiquilin-1
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0016236 macroautophagy IMP
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0031396 regulation of protein ubiquitination IDA
 biological_processGO:0031398 positive regulation of protein ubiquitination IDA
 biological_processGO:0034140 negative regulation of toll-like receptor 3 signaling pathway IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IMP
 biological_processGO:0035973 aggrephagy IDA
 biological_processGO:0071456 cellular response to hypoxia IMP
 biological_processGO:0097352 autophagosome maturation IMP
 biological_processGO:1901340 negative regulation of store-operated calcium channel activity IMP
 biological_processGO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IMP
 biological_processGO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process IMP
 cellular_componentGO:0000502 proteasome complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IMP
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016235 aggresome IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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