ENSG00000135116


Homo sapiens

Features
Gene ID: ENSG00000135116
  
Biological name :HRK
  
Synonyms : harakiri, BCL2 interacting protein / HRK / O00198
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.22
Gene start: 116856144
Gene end: 116881441
  
Corresponding Affymetrix probe sets: 206864_s_at (Human Genome U133 Plus 2.0 Array)   206865_at (Human Genome U133 Plus 2.0 Array)   229552_at (Human Genome U133 Plus 2.0 Array)   237187_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000257572
Ensembl peptide - ENSP00000465379
NCBI entrez gene - 8739     See in Manteia.
OMIM - 603447
RefSeq - XM_017020146
RefSeq - NM_003806
RefSeq Peptide - NP_003797
swissprot - O00198
swissprot - K7EJY7
Ensembl - ENSG00000135116
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HrkENSMUSG00000046607Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR017249  Activator of apoptosis harakiri
 IPR020728  Apoptosis regulator, Bcl-2, BH3 motif, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0032464 positive regulation of protein homooligomerization IDA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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