ENSG00000135624


Homo sapiens

Features
Gene ID: ENSG00000135624
  
Biological name :CCT7
  
Synonyms : CCT7 / chaperonin containing TCP1 subunit 7 / Q99832
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.2
Gene start: 73233420
Gene end: 73253021
  
Corresponding Affymetrix probe sets: 200812_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000442058
Ensembl peptide - ENSP00000437824
Ensembl peptide - ENSP00000487267
Ensembl peptide - ENSP00000258091
Ensembl peptide - ENSP00000381456
Ensembl peptide - ENSP00000386978
Ensembl peptide - ENSP00000412996
NCBI entrez gene - 10574     See in Manteia.
OMIM - 605140
RefSeq - XM_011532479
RefSeq - NM_001009570
RefSeq - NM_001166284
RefSeq - NM_001166285
RefSeq - NM_006429
RefSeq - XM_011532478
RefSeq Peptide - NP_001159756
RefSeq Peptide - NP_001159757
RefSeq Peptide - NP_006420
RefSeq Peptide - NP_001009570
swissprot - Q99832
swissprot - F8WAM2
swissprot - F8WBP8
swissprot - A0A0D9SG95
Ensembl - ENSG00000135624
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct7ENSDARG00000007385Danio rerio
 CCT7ENSGALG00000016088Gallus gallus
 Cct7ENSMUSG00000030007Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001844  Chaperonin Cpn60
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012720  T-complex protein 1, eta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IEA
 biological_processGO:0032212 positive regulation of telomere maintenance via telomerase IMP
 biological_processGO:0042026 protein refolding IEA
 biological_processGO:0050821 protein stabilization IMP
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1904851 positive regulation of establishment of protein localization to telomere IMP
 biological_processGO:1904871 positive regulation of protein localization to Cajal body IMP
 biological_processGO:1904874 positive regulation of telomerase RNA localization to Cajal body IMP
 cellular_componentGO:0002199 zona pellucida receptor complex IEA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005832 chaperonin-containing T-complex TAS
 cellular_componentGO:0005874 microtubule IDA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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