ENSG00000135926


Homo sapiens

Features
Gene ID: ENSG00000135926
  
Biological name :TMBIM1
  
Synonyms : Q969X1 / TMBIM1 / transmembrane BAX inhibitor motif containing 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q35
Gene start: 218274192
Gene end: 218292586
  
Corresponding Affymetrix probe sets: 217730_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394946
Ensembl peptide - ENSP00000380025
Ensembl peptide - ENSP00000395614
Ensembl peptide - ENSP00000414572
Ensembl peptide - ENSP00000413624
Ensembl peptide - ENSP00000412518
Ensembl peptide - ENSP00000410771
Ensembl peptide - ENSP00000410136
Ensembl peptide - ENSP00000409738
Ensembl peptide - ENSP00000408729
Ensembl peptide - ENSP00000406744
Ensembl peptide - ENSP00000405516
Ensembl peptide - ENSP00000404709
Ensembl peptide - ENSP00000403462
Ensembl peptide - ENSP00000401491
Ensembl peptide - ENSP00000399987
Ensembl peptide - ENSP00000399345
Ensembl peptide - ENSP00000258412
NCBI entrez gene - 64114     See in Manteia.
OMIM - 610364
RefSeq - NM_001321436
RefSeq - NM_001321427
RefSeq - NM_001321428
RefSeq - NM_001321429
RefSeq - NM_001321430
RefSeq - NM_001321432
RefSeq - NM_001321433
RefSeq - NM_001321435
RefSeq - NM_001321438
RefSeq - NM_022152
RefSeq - XM_011511627
RefSeq Peptide - NP_001308361
RefSeq Peptide - NP_001308362
RefSeq Peptide - NP_001308364
RefSeq Peptide - NP_001308365
RefSeq Peptide - NP_001308367
RefSeq Peptide - NP_001308358
RefSeq Peptide - NP_071435
RefSeq Peptide - NP_001308359
RefSeq Peptide - NP_001308356
RefSeq Peptide - NP_001308357
swissprot - C9JM62
swissprot - C9JI44
swissprot - C9JEN3
swissprot - C9JDV0
swissprot - C9JAP5
swissprot - C9JAK9
swissprot - C9IYT2
swissprot - C9IZ27
swissprot - B4DUD2
swissprot - B3KSM0
swissprot - A0A1D5RMQ2
swissprot - F8WDY4
swissprot - A0A024R472
swissprot - Q969X1
swissprot - C9JWV9
swissprot - C9JW19
swissprot - C9JN47
Ensembl - ENSG00000135926
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmbim1aENSDARG00000058323Danio rerio
 tmbim1bENSDARG00000109373Danio rerio
 TMBIM1ENSGALG00000011436Gallus gallus
 Tmbim1ENSMUSG00000006301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FAIM2 / Q9BWQ8 / Fas apoptotic inhibitory molecule 2ENSG0000013547249
GRINA / Q7Z429 / glutamate ionotropic receptor NMDA type subunit associated protein 1ENSG0000017871943
Q9HC24 / TMBIM4 / transmembrane BAX inhibitor motif containing 4ENSG0000015595721
AC078927.1ENSG0000022814414


Protein motifs (from Interpro)
Interpro ID Name
 IPR006214  Bax inhibitor 1-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043086 negative regulation of catalytic activity ISS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IMP
 biological_processGO:1902045 negative regulation of Fas signaling pathway IMP
 biological_processGO:1903077 negative regulation of protein localization to plasma membrane IMP
 biological_processGO:2000504 positive regulation of blood vessel remodeling ISS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005123 death receptor binding IDA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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