ENSG00000135932


Homo sapiens

Features
Gene ID: ENSG00000135932
  
Biological name :CAB39
  
Synonyms : CAB39 / calcium binding protein 39 / Q9Y376
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 230712845
Gene end: 230821075
  
Corresponding Affymetrix probe sets: 217873_at (Human Genome U133 Plus 2.0 Array)   224311_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258418
Ensembl peptide - ENSP00000483459
Ensembl peptide - ENSP00000386642
Ensembl peptide - ENSP00000386238
NCBI entrez gene - 51719     See in Manteia.
OMIM - 612174
RefSeq - NM_001130849
RefSeq - NM_001130850
RefSeq - NM_016289
RefSeq Peptide - NP_001124321
RefSeq Peptide - NP_057373
RefSeq Peptide - NP_001124322
swissprot - Q9Y376
swissprot - A0A024R496
swissprot - A0A087X0K1
Ensembl - ENSG00000135932
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cab39ENSDARG00000043451Danio rerio
 CAB39ENSGALG00000027262Gallus gallus
 Cab39ENSMUSG00000036707Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CAB39L / Q9H9S4 / calcium binding protein 39 likeENSG0000010254780


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR013878  Mo25-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation IDA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0023014 signal transduction by protein phosphorylation IDA
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0071476 cellular hypotonic response IC
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IDA
 biological_processGO:1901017 negative regulation of potassium ion transmembrane transporter activity IC
 biological_processGO:1901380 negative regulation of potassium ion transmembrane transport IC
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1902554 serine/threonine protein kinase complex IC
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0030295 protein kinase activator activity IDA
 molecular_functionGO:0043539 protein serine/threonine kinase activator activity IDA


Pathways (from Reactome)
Pathway description
Energy dependent regulation of mTOR by LKB1-AMPK
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000082146 Q9C0K7 / STRADB / STE20-related kinase adaptor beta  / complex / reaction
 ENSG00000266173 Q7RTN6 / STRADA / STE20-related kinase adaptor alpha  / complex / reaction
 ENSG00000118046 STK11 / Q15831 / serine/threonine kinase 11  / complex / reaction






 

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