ENSG00000082146


Homo sapiens

Features
Gene ID: ENSG00000082146
  
Biological name :STRADB
  
Synonyms : Q9C0K7 / STE20-related kinase adaptor beta / STRADB
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q33.1
Gene start: 201387858
Gene end: 201480846
  
Corresponding Affymetrix probe sets: 223266_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413574
Ensembl peptide - ENSP00000376080
Ensembl peptide - ENSP00000404359
Ensembl peptide - ENSP00000409552
Ensembl peptide - ENSP00000194530
NCBI entrez gene - 55437     See in Manteia.
OMIM - 607333
RefSeq - XM_017004438
RefSeq - NM_001206864
RefSeq - NM_018571
RefSeq - XM_005246669
RefSeq Peptide - NP_061041
RefSeq Peptide - NP_001193793
swissprot - H7C3S5
swissprot - Q9C0K7
swissprot - C9JSU7
swissprot - F8WCQ7
swissprot - A0A024R420
Ensembl - ENSG00000082146
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO082877.1ENSDARG00000088225Danio rerio
 STRADBENSGALG00000008373Gallus gallus
 Q8K4T3ENSMUSG00000026027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7RTN6 / STRADA / STE20-related kinase adaptor alphaENSG0000026617344
OXSR1 / O95747 / oxidative stress responsive 1ENSG0000017293926
STK39 / Q9UEW8 / serine/threonine kinase 39ENSG0000019864825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006611 protein export from nucleus IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest TAS
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016235 aggresome IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Energy dependent regulation of mTOR by LKB1-AMPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118046 STK11 / Q15831 / serine/threonine kinase 11  / reaction / complex
 ENSG00000102547 CAB39L / Q9H9S4 / calcium binding protein 39 like  / reaction / complex
 ENSG00000135932 CAB39 / Q9Y376 / calcium binding protein 39  / complex / reaction






 

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