ENSG00000172939


Homo sapiens

Features
Gene ID: ENSG00000172939
  
Biological name :OXSR1
  
Synonyms : O95747 / oxidative stress responsive 1 / OXSR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.2
Gene start: 38165089
Gene end: 38255488
  
Corresponding Affymetrix probe sets: 202696_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000398356
Ensembl peptide - ENSP00000415851
Ensembl peptide - ENSP00000311713
NCBI entrez gene - 9943     See in Manteia.
OMIM - 604046
RefSeq - XM_017007602
RefSeq - NM_005109
RefSeq - XM_005265638
RefSeq - XM_011534331
RefSeq - XM_017007601
RefSeq Peptide - NP_005100
swissprot - O95747
swissprot - C9JIG9
swissprot - F8WBK9
swissprot - A0A024R2M7
Ensembl - ENSG00000172939
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oxsr1aENSDARG00000034189Danio rerio
 oxsr1bENSDARG00000027500Danio rerio
 OXSR1ENSGALG00000005979Gallus gallus
 Oxsr1ENSMUSG00000036737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STK39 / Q9UEW8 / serine/threonine kinase 39ENSG0000019864874
Q7RTN6 / STRADA / STE20-related kinase adaptor alphaENSG0000026617322
Q9C0K7 / STRADB / STE20-related kinase adaptor betaENSG0000008214620


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain
 IPR028749  Serine/threonine-protein kinase OSR1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006979 response to oxidative stress TAS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0023014 signal transduction by protein phosphorylation IEA
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0071476 cellular hypotonic response IEA
 biological_processGO:1901017 negative regulation of potassium ion transmembrane transporter activity IEA
 biological_processGO:1901380 negative regulation of potassium ion transmembrane transport IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr