ENSG00000198648


Homo sapiens

Features
Gene ID: ENSG00000198648
  
Biological name :STK39
  
Synonyms : Q9UEW8 / serine/threonine kinase 39 / STK39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q24.3
Gene start: 167954020
Gene end: 168248141
  
Corresponding Affymetrix probe sets: 202786_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000348278
NCBI entrez gene - 27347     See in Manteia.
OMIM - 607648
RefSeq - XM_017003817
RefSeq - NM_013233
RefSeq - XM_017003814
RefSeq - XM_017003815
RefSeq - XM_005246465
RefSeq - XM_017003813
RefSeq Peptide - NP_037365
swissprot - Q9UEW8
Ensembl - ENSG00000198648
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stk39ENSDARG00000087203Danio rerio
 STK39ENSGALG00000010930Gallus gallus
 Stk39ENSMUSG00000027030Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OXSR1 / O95747 / oxidative stress responsive 1ENSG0000017293972
Q7RTN6 / STRADA / STE20-related kinase adaptor alphaENSG0000026617320
Q9C0K7 / STRADB / STE20-related kinase adaptor betaENSG0000008214619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR024678  Serine/threonine-protein kinase OSR1/WNK, CCT domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation ISS
 biological_processGO:0007346 regulation of mitotic cell cycle IBA
 biological_processGO:0008217 regulation of blood pressure IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IEA
 biological_processGO:0023014 signal transduction by protein phosphorylation IDA
 biological_processGO:0023016 signal transduction by trans-phosphorylation IMP
 biological_processGO:0031098 stress-activated protein kinase signaling cascade IBA
 biological_processGO:0032147 activation of protein kinase activity IBA
 biological_processGO:0032414 positive regulation of ion transmembrane transporter activity IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0036438 maintenance of lens transparency IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043268 positive regulation of potassium ion transport IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 biological_processGO:0071476 cellular hypotonic response IC
 biological_processGO:0090188 negative regulation of pancreatic juice secretion IEA
 biological_processGO:1901017 negative regulation of potassium ion transmembrane transporter activity IDA
 biological_processGO:1901380 negative regulation of potassium ion transmembrane transport IDA
 biological_processGO:1905408 negative regulation of creatine transmembrane transporter activity IDA
 biological_processGO:2000650 negative regulation of sodium ion transmembrane transporter activity IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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