ENSG00000136021


Homo sapiens

Features
Gene ID: ENSG00000136021
  
Biological name :SCYL2
  
Synonyms : Q6P3W7 / SCY1 like pseudokinase 2 / SCYL2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q23.1
Gene start: 100267140
Gene end: 100341724
  
Corresponding Affymetrix probe sets: 221220_s_at (Human Genome U133 Plus 2.0 Array)   224960_at (Human Genome U133 Plus 2.0 Array)   224961_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000450294
Ensembl peptide - ENSP00000449567
Ensembl peptide - ENSP00000489123
Ensembl peptide - ENSP00000354061
Ensembl peptide - ENSP00000448366
Ensembl peptide - ENSP00000448400
NCBI entrez gene - 55681     See in Manteia.
OMIM - 616365
RefSeq - XM_017019620
RefSeq - NM_001317784
RefSeq - NM_001330253
RefSeq - NM_001330254
RefSeq - NM_017988
RefSeq - XM_017019618
RefSeq - XM_017019619
RefSeq Peptide - NP_001304713
RefSeq Peptide - NP_001317182
RefSeq Peptide - NP_001317183
RefSeq Peptide - NP_060458
swissprot - H0YI32
swissprot - H0YIK6
swissprot - F8VSC5
swissprot - A0A0U1RQQ9
swissprot - F8VPW3
swissprot - Q6P3W7
Ensembl - ENSG00000136021
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SCYL2ENSDARG00000032627Danio rerio
 SCYL2ENSGALG00000011569Gallus gallus
 Scyl2ENSMUSG00000069539Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002092 positive regulation of receptor internalization IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008333 endosome to lysosome transport IDA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IDA
 biological_processGO:2000286 receptor internalization involved in canonical Wnt signaling pathway IDA
 biological_processGO:2000370 positive regulation of clathrin-dependent endocytosis IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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