ENSG00000136026


Homo sapiens

Features
Gene ID: ENSG00000136026
  
Biological name :CKAP4
  
Synonyms : CKAP4 / cytoskeleton associated protein 4 / Q07065
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q23.3
Gene start: 106237877
Gene end: 106304279
  
Corresponding Affymetrix probe sets: 200998_s_at (Human Genome U133 Plus 2.0 Array)   200999_s_at (Human Genome U133 Plus 2.0 Array)   226526_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449240
Ensembl peptide - ENSP00000367265
NCBI entrez gene - 10970     See in Manteia.
RefSeq - NM_006825
RefSeq Peptide - NP_006816
swissprot - Q07065
swissprot - A0A024RBH2
swissprot - F8VVU0
Ensembl - ENSG00000136026
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:85975ENSDARG00000032405Danio rerio
 CKAP4ENSGALG00000012659Gallus gallus
 Ckap4ENSMUSG00000046841Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028428  Cytoskeleton-associated protein 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IDA
 cellular_componentGO:0005811 lipid droplet IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IDA
 cellular_componentGO:0042599 lamellar body TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding HDA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Surfactant metabolism
Neutrophil degranulation
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104219 Q9UIJ5 / ZDHHC2 / zinc finger DHHC-type containing 2  / reaction
 ENSG00000229415 SFTA3 / P0C7M3 / surfactant associated 3  / complex / reaction
 ENSG00000185303 Q8IWL1 / SFTPA2 / surfactant protein A2  / reaction / complex
 ENSG00000122852 Q8IWL2 / SFTPA1 / surfactant protein A1  / complex / reaction






 

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