ENSG00000136159


Homo sapiens

Features
Gene ID: ENSG00000136159
  
Biological name :NUDT15
  
Synonyms : nudix hydrolase 15 / NUDT15 / Q9NV35
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q14.2
Gene start: 48037567
Gene end: 48047222
  
Corresponding Affymetrix probe sets: 219347_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000258662
NCBI entrez gene - 55270     See in Manteia.
OMIM - 615792
RefSeq - NM_018283
RefSeq Peptide - NP_060753
swissprot - Q9NV35
Ensembl - ENSG00000136159
  
Related genetic diseases (OMIM): 616903 - {Thiopurines, poor metabolism of, 2}, 616903
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt15ENSDARG00000113961Danio rerio
 NUDT15ENSGALG00000016994Gallus gallus
 Gm5519ENSMUSG00000037603Mus musculus
 Nudt15ENSMUSG00000033405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0006195 purine nucleotide catabolic process IMP
 biological_processGO:0006203 dGTP catabolic process IDA
 biological_processGO:0034656 nucleobase-containing small molecule catabolic process TAS
 biological_processGO:0042262 DNA protection IMP
 biological_processGO:0042738 exogenous drug catabolic process IMP
 biological_processGO:0061136 regulation of proteasomal protein catabolic process IMP
 biological_processGO:1901292 nucleoside phosphate catabolic process IMP
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004551 nucleotide diphosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity EXP
 molecular_functionGO:0035529 NADH pyrophosphatase activity IEA
 molecular_functionGO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity EXP
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047429 nucleoside-triphosphate diphosphatase activity IDA


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NUDT proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr