ENSMUSG00000033405


Mus musculus

Features
Gene ID: ENSMUSG00000033405
  
Biological name :Nudt15
  
Synonyms : Nucleotide triphosphate diphosphatase NUDT15 / Nudt15 / Q8BG93
  
Possible biological names infered from orthology : nudix hydrolase 15 / Q9NV35
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D3
Gene start: 73518877
Gene end: 73548242
  
Corresponding Affymetrix probe sets: 10421567 (MoGene1.0st)   10462539 (MoGene1.0st)   10472195 (MoGene1.0st)   1437215_at (Mouse Genome 430 2.0 Array)   1455969_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000039537
NCBI entrez gene - 214254     See in Manteia.
MGI - MGI:2443366
RefSeq - NM_172527
RefSeq - XM_017315941
RefSeq Peptide - NP_766115
swissprot - Q8BG93
Ensembl - ENSMUSG00000033405
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nudt15ENSDARG00000113961Danio rerio
 NUDT15ENSGALG00000016994Gallus gallus
 NUDT15ENSG00000136159Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm5519 / NUDT15* / Q9NV35* / nudix hydrolase 15*ENSMUSG0000003760397


Protein motifs (from Interpro)
Interpro ID Name
 IPR000086  NUDIX hydrolase domain
 IPR015797  NUDIX hydrolase-like domain superfamily
 IPR020084  NUDIX hydrolase, conserved site
 IPR020476  NUDIX hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle ISS
 biological_processGO:0000302 response to reactive oxygen species IDA
 biological_processGO:0006195 purine nucleotide catabolic process ISS
 biological_processGO:0006203 dGTP catabolic process ISS
 biological_processGO:0009217 purine deoxyribonucleoside triphosphate catabolic process IDA
 biological_processGO:0042738 exogenous drug catabolic process ISO
 biological_processGO:0061136 regulation of proteasomal protein catabolic process ISO
 biological_processGO:1901292 nucleoside phosphate catabolic process ISO
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004551 nucleotide diphosphatase activity IEA
 molecular_functionGO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017110 nucleoside-diphosphatase activity ISO
 molecular_functionGO:0035529 NADH pyrophosphatase activity IEA
 molecular_functionGO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0047429 nucleoside-triphosphate diphosphatase activity ISO


Pathways (from Reactome)
Pathway description
Phosphate bond hydrolysis by NUDT proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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