ENSG00000136856


Homo sapiens

Features
Gene ID: ENSG00000136856
  
Biological name :SLC2A8
  
Synonyms : Q9NY64 / SLC2A8 / solute carrier family 2 member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q33.3
Gene start: 127397138
Gene end: 127408424
  
Corresponding Affymetrix probe sets: 218985_at (Human Genome U133 Plus 2.0 Array)   239426_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411726
Ensembl peptide - ENSP00000404893
Ensembl peptide - ENSP00000413973
Ensembl peptide - ENSP00000477568
Ensembl peptide - ENSP00000362450
Ensembl peptide - ENSP00000362458
Ensembl peptide - ENSP00000362469
Ensembl peptide - ENSP00000389070
Ensembl peptide - ENSP00000391213
Ensembl peptide - ENSP00000392434
NCBI entrez gene - 29988     See in Manteia.
OMIM - 605245
RefSeq - XM_017014653
RefSeq - NM_001271711
RefSeq - NM_001271712
RefSeq - NM_014580
RefSeq - XM_006717084
RefSeq - XM_011518602
RefSeq - XM_011518603
RefSeq - XM_011518604
RefSeq Peptide - NP_055395
RefSeq Peptide - NP_001258640
RefSeq Peptide - NP_001258641
swissprot - Q5VVV5
swissprot - Q5VVV6
swissprot - Q5VVV9
swissprot - Q5VVW0
swissprot - A0A087WT42
swissprot - H0Y7M6
swissprot - Q5VVW5
swissprot - Q9NY64
swissprot - A0A024R871
swissprot - Q5VVV3
swissprot - Q5VVV4
Ensembl - ENSG00000136856
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc2a8ENSDARG00000104278Danio rerio
 SLC2A8ENSGALG00000000853Gallus gallus
 Q9JIF3ENSMUSG00000026791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UGQ3 / SLC2A6 / solute carrier family 2 member 6ENSG0000016032643
Q96QE2 / SLC2A13 / solute carrier family 2 member 13ENSG0000015122931
Q8TD20 / SLC2A12 / solute carrier family 2 member 12ENSG0000014641129
O95528 / SLC2A10 / solute carrier family 2 member 10ENSG0000019749628


Protein motifs (from Interpro)
Interpro ID Name
 IPR003663  Sugar/inositol transporter
 IPR005828  Major facilitator, sugar transporter-like
 IPR005829  Sugar transporter, conserved site
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0005975 carbohydrate metabolic process TAS
 biological_processGO:0007141 male meiosis I IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0008643 carbohydrate transport IEA
 biological_processGO:0008645 hexose transmembrane transport TAS
 biological_processGO:0046323 glucose import IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:1902600 proton transmembrane transport IEA
 biological_processGO:1904659 glucose transmembrane transport TAS
 cellular_componentGO:0005765 lysosomal membrane HDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005215 transporter activity IEA
 molecular_functionGO:0005351 carbohydrate:proton symporter activity IBA
 molecular_functionGO:0005355 glucose transmembrane transporter activity TAS
 molecular_functionGO:0005536 glucose binding IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0055056 D-glucose transmembrane transporter activity TAS


Pathways (from Reactome)
Pathway description
Cellular hexose transport
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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