ENSG00000136870


Homo sapiens

Features
Gene ID: ENSG00000136870
  
Biological name :ZNF189
  
Synonyms : O75820 / zinc finger protein 189 / ZNF189
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q31.1
Gene start: 101398873
Gene end: 101410660
  
Corresponding Affymetrix probe sets: 207513_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000483461
Ensembl peptide - ENSP00000259395
Ensembl peptide - ENSP00000342019
Ensembl peptide - ENSP00000363995
NCBI entrez gene - 7743     See in Manteia.
OMIM - 603132
RefSeq - XM_017015121
RefSeq - NM_001278231
RefSeq - NM_001278232
RefSeq - NM_001278240
RefSeq - NM_003452
RefSeq - NM_197977
RefSeq - XM_006717280
RefSeq - XM_006717281
RefSeq - XM_011518998
RefSeq Peptide - NP_001265161
RefSeq Peptide - NP_001265169
RefSeq Peptide - NP_932094
RefSeq Peptide - NP_003443
RefSeq Peptide - NP_001265160
swissprot - A0A087X0K2
swissprot - O75820
Ensembl - ENSG00000136870
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT027801.1ENSDARG00000096005Danio rerio
 Zfp189ENSMUSG00000039634Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q99676 / ZNF184 / zinc finger protein 184ENSG0000009665447
P52742 / ZNF135 / zinc finger protein 135ENSG0000017629346
ZNF23 / P17027 / zinc finger protein 23ENSG0000016737746
Q5MCW4 / ZNF569 / zinc finger protein 569ENSG0000019643746
Q6ECI4 / ZNF470 / zinc finger protein 470ENSG0000019701646
ZNF16 / P17020 / zinc finger protein 16ENSG0000017063145
Q9H7R5 / ZNF665 / zinc finger protein 665ENSG0000019749745
Q9HBT7 / ZNF287 / zinc finger protein 287ENSG0000014104043
B4DU55 / ZNF879 / zinc finger protein 879ENSG0000023428442
Q76KX8 / ZNF534 / zinc finger protein 534ENSG0000019863342
Q86YE8 / ZNF573 / zinc finger protein 573ENSG0000018914442
ZNF83 / P51522 / zinc finger protein 83ENSG0000016776639
Q9P0L1 / ZKSCAN7 / zinc finger with KRAB and SCAN domains 7ENSG0000019634538
Q5SXM1 / ZNF678 / zinc finger protein 678ENSG0000018145036
ZNF71 / Q9NQZ8 / zinc finger protein 71ENSG0000019795135
ZFP3 / Q96NJ6 / ZFP3 zinc finger proteinENSG0000018078735
ZFP2 / Q6ZN57 / ZFP2 zinc finger proteinENSG0000019893935
O75290 / ZNF780A / zinc finger protein 780AENSG0000019778234
P0CG24 / ZNF883 / zinc finger protein 883ENSG0000028544734
Q6ZMS4 / ZNF852 / zinc finger protein 852ENSG0000017891734


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr