ENSG00000137135


Homo sapiens

Features
Gene ID: ENSG00000137135
  
Biological name :ARHGEF39
  
Synonyms : ARHGEF39 / Q8N4T4 / Rho guanine nucleotide exchange factor 39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p13.3
Gene start: 35658875
Gene end: 35675866
  
Corresponding Affymetrix probe sets: 230521_at (Human Genome U133 Plus 2.0 Array)   230522_s_at (Human Genome U133 Plus 2.0 Array)   231892_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367638
Ensembl peptide - ENSP00000436519
Ensembl peptide - ENSP00000436756
NCBI entrez gene - 84904     See in Manteia.
RefSeq - XM_017015228
RefSeq - NM_032818
RefSeq - XM_017015226
RefSeq - XM_017015227
RefSeq - XM_011518057
RefSeq - XM_017015225
RefSeq Peptide - NP_116207
swissprot - Q8N4T4
Ensembl - ENSG00000137135
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef39ENSDARG00000013476Danio rerio
 ARHGEF39ENSGALG00000002599Gallus gallus
 Q66JY6ENSMUSG00000051517Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030335 positive regulation of cell migration IDA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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