ENSG00000137270


Homo sapiens

Features
Gene ID: ENSG00000137270
  
Biological name :GCM1
  
Synonyms : GCM1 / glial cells missing homolog 1 / Q9NP62
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.1
Gene start: 53126964
Gene end: 53148829
  
Corresponding Affymetrix probe sets: 206269_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000259803
NCBI entrez gene - 8521     See in Manteia.
OMIM - 603715
RefSeq - NM_003643
RefSeq - XM_017011390
RefSeq Peptide - NP_003634
swissprot - Q9NP62
Ensembl - ENSG00000137270
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCM1ENSGALG00000016316Gallus gallus
 Gcm1ENSMUSG00000023333Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GCM2 / O75603 / glial cells missing homolog 2ENSG0000012482732


Protein motifs (from Interpro)
Interpro ID Name
 IPR003902  Transcription regulator GCM domain
 IPR036115  GCM domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II IDA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009653 anatomical structure morphogenesis TAS
 biological_processGO:0042063 gliogenesis IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060018 astrocyte fate commitment IEA
 biological_processGO:0060143 positive regulation of syncytium formation by plasma membrane fusion IEA
 biological_processGO:0060670 branching involved in labyrinthine layer morphogenesis IEA
 biological_processGO:0060706 cell differentiation involved in embryonic placenta development IEA
 biological_processGO:0060800 regulation of cell differentiation involved in embryonic placenta development IMP
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005667 transcription factor complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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