ENSG00000137492


Homo sapiens

Features
Gene ID: ENSG00000137492
  
Biological name :THAP12
  
Synonyms : O43422 / THAP12 / THAP domain containing 12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.5
Gene start: 76349956
Gene end: 76380971
  
Corresponding Affymetrix probe sets: 209323_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260045
Ensembl peptide - ENSP00000433966
NCBI entrez gene - 5612     See in Manteia.
OMIM - 607374
RefSeq - NM_004705
RefSeq Peptide - NP_004696
swissprot - E9PSI2
swissprot - A0A140VJQ7
swissprot - O43422
Ensembl - ENSG00000137492
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 thap12aENSDARG00000042489Danio rerio
 thap12bENSDARG00000020964Danio rerio
 THAP12ENSGALG00000000838Gallus gallus
 Q9CUX1ENSMUSG00000030753Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006612  THAP-type zinc finger
 IPR008906  HAT, C-terminal dimerisation domain
 IPR012337  Ribonuclease H-like superfamily
 IPR025398  Domain of unknown function DUF4371


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr