ENSG00000138433


Homo sapiens

Features
Gene ID: ENSG00000138433
  
Biological name :CIR1
  
Synonyms : CIR1 / corepressor interacting with RBPJ, 1 / Q86X95
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q31.1
Gene start: 174348022
Gene end: 174395715
  
Corresponding Affymetrix probe sets: 209571_at (Human Genome U133 Plus 2.0 Array)   1440525_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000339723
Ensembl peptide - ENSP00000367211
NCBI entrez gene - 9541     See in Manteia.
OMIM - 605228
RefSeq - NM_004882
RefSeq Peptide - NP_004873
swissprot - Q86X95
swissprot - H3BLY3
Ensembl - ENSG00000138433
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CIR1ENSDARG00000099733Danio rerio
 CIR1ENSGALG00000014276Gallus gallus
 Cir1ENSMUSG00000041777Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019339  CBF1-interacting co-repressor CIR, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0000118 histone deacetylase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding TAS
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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