ENSG00000138663


Homo sapiens

Features
Gene ID: ENSG00000138663
  
Biological name :COPS4
  
Synonyms : COP9 signalosome subunit 4 / COPS4 / Q9BT78
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q21.22
Gene start: 83034447
Gene end: 83075818
  
Corresponding Affymetrix probe sets: 218042_at (Human Genome U133 Plus 2.0 Array)   237649_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000264389
Ensembl peptide - ENSP00000426788
Ensembl peptide - ENSP00000425976
Ensembl peptide - ENSP00000425486
Ensembl peptide - ENSP00000424791
Ensembl peptide - ENSP00000424655
NCBI entrez gene - 51138     See in Manteia.
OMIM - 616008
RefSeq - XM_011532019
RefSeq - NM_001258006
RefSeq - NM_016129
RefSeq Peptide - NP_057213
RefSeq Peptide - NP_001244935
RefSeq Peptide - NP_001317656
swissprot - D6RFN0
swissprot - D6RD63
swissprot - A0A0S2Z5H7
swissprot - D6RAX7
swissprot - D6REK7
swissprot - Q9BT78
Ensembl - ENSG00000138663
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cops4ENSDARG00000043732Danio rerio
 COPS4ENSGALG00000011130Gallus gallus
 Cops4ENSMUSG00000035297Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000338 protein deneddylation IMP
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition TAS
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019784 NEDD8-specific protease activity IBA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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