ENSG00000138801


Homo sapiens

Features
Gene ID: ENSG00000138801
  
Biological name :PAPSS1
  
Synonyms : 3-phosphoadenosine 5-phosphosulfate synthase 1 / O43252 / PAPSS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q25
Gene start: 107590276
Gene end: 107720452
  
Corresponding Affymetrix probe sets: 209043_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000265174
NCBI entrez gene - 9061     See in Manteia.
OMIM - 603262
RefSeq - XM_011532401
RefSeq - NM_005443
RefSeq - XM_011532400
RefSeq Peptide - NP_005434
swissprot - O43252
Ensembl - ENSG00000138801
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 papss1ENSDARG00000057099Danio rerio
 PAPSS1ENSGALG00000010542Gallus gallus
 Papss1ENSMUSG00000028032Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O95340 / PAPSS2 / 3-phosphoadenosine 5-phosphosulfate synthase 2ENSG0000019868273


Protein motifs (from Interpro)
Interpro ID Name
 IPR002650  Sulphate adenylyltransferase
 IPR002891  Adenylyl-sulfate kinase
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR015947  PUA-like superfamily
 IPR024951  Sulphate adenylyltransferase catalytic domain
 IPR025980  ATP-sulfurylase PUA-like domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000103 sulfate assimilation IDA
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0050428 3"-phosphoadenosine 5"-phosphosulfate biosynthetic process TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004020 adenylylsulfate kinase activity TAS
 molecular_functionGO:0004781 sulfate adenylyltransferase (ATP) activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity ISS
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Transport and synthesis of PAPS
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se
Signaling by BRAF and RAF fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000138801 O43252 / PAPSS1 / 3-phosphoadenosine 5-phosphosulfate synthase 1  / complex






 

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