ENSG00000139289


Homo sapiens

Features
Gene ID: ENSG00000139289
  
Biological name :PHLDA1
  
Synonyms : PHLDA1 / pleckstrin homology like domain family A member 1 / Q8WV24
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q21.2
Gene start: 76025447
Gene end: 76033932
  
Corresponding Affymetrix probe sets: 217996_at (Human Genome U133 Plus 2.0 Array)   217997_at (Human Genome U133 Plus 2.0 Array)   217998_at (Human Genome U133 Plus 2.0 Array)   217999_s_at (Human Genome U133 Plus 2.0 Array)   218000_s_at (Human Genome U133 Plus 2.0 Array)   225842_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473593
Ensembl peptide - ENSP00000480767
Ensembl peptide - ENSP00000266671
NCBI entrez gene - 22822     See in Manteia.
OMIM - 605335
RefSeq - NM_007350
RefSeq Peptide - NP_031376
swissprot - Q8WV24
swissprot - R4GND3
Ensembl - ENSG00000139289
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phlda1ENSDARG00000099129Danio rerio
 PHLDA1ENSGALG00000034788Gallus gallus
 Phlda1ENSMUSG00000020205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHLDA3 / Q9Y5J5 / pleckstrin homology like domain family A member 3ENSG0000017430716
PHLDA2 / Q53GA4 / pleckstrin homology like domain family A member 2ENSG0000018164915


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0045210 FasL biosynthetic process IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Interaction between PHLDA1 and AURKA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000087586 AURKA / O14965 / aurora kinase A  / complex / reaction






 

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