ENSG00000139610


Homo sapiens

Features
Gene ID: ENSG00000139610
  
Biological name :CELA1
  
Synonyms : CELA1 / chymotrypsin like elastase family member 1 / Q9UNI1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 51328443
Gene end: 51346679
  
Corresponding Affymetrix probe sets: 224198_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000293636
NCBI entrez gene - 1990     See in Manteia.
OMIM - 130120
RefSeq - NM_001971
RefSeq Peptide - NP_001962
swissprot - Q9UNI1
Ensembl - ENSG00000139610
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-57c15.4ENSDARG00000095462Danio rerio
 zgc:112302ENSDARG00000043171Danio rerio
 zgc:112368ENSDARG00000043175Danio rerio
 zgc:92041ENSDARG00000017314Danio rerio
 zgc:92511ENSDARG00000077058Danio rerio
 zgc:92511ENSDARG00000043168Danio rerio
 zgc:92745ENSDARG00000043173Danio rerio
 ENSGALG00000034825Gallus gallus
 CELA1ENSGALG00000034809Gallus gallus
 Cela1ENSMUSG00000023031Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CELA2A / P08217 / chymotrypsin like elastase family member 2AENSG0000014261556
CELA2B / P08218 / chymotrypsin like elastase family member 2BENSG0000021570455
CELA3A / P09093 / chymotrypsin like elastase family member 3AENSG0000014278954
CELA3B / P08861 / chymotrypsin like elastase family member 3BENSG0000021907353
CTRC / Q99895 / chymotrypsin CENSG0000016243848
CTRL / P40313 / chymotrypsin likeENSG0000014108638
CTRB1 / P17538 / chymotrypsinogen B1ENSG0000016892535
CTRB2 / Q6GPI1 / chymotrypsinogen B2ENSG0000016892835
OVCH2 / ovochymase 2 (gene/pseudogene)ENSG0000018337834
OVCH1 / Q7RTY7 / ovochymase 1ENSG0000018795032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0031017 exocrine pancreas development IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048771 tissue remodeling IEA
 biological_processGO:0055123 digestive system development IEA
 biological_processGO:0060309 elastin catabolic process IEA
 biological_processGO:0061113 pancreas morphogenesis IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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