ENSG00000139644


Homo sapiens

Features
Gene ID: ENSG00000139644
  
Biological name :TMBIM6
  
Synonyms : P55061 / TMBIM6 / transmembrane BAX inhibitor motif containing 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.12
Gene start: 49707725
Gene end: 49764934
  
Corresponding Affymetrix probe sets: 200803_s_at (Human Genome U133 Plus 2.0 Array)   200804_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000447074
Ensembl peptide - ENSP00000267115
Ensembl peptide - ENSP00000378454
Ensembl peptide - ENSP00000389277
Ensembl peptide - ENSP00000446668
Ensembl peptide - ENSP00000446734
Ensembl peptide - ENSP00000447030
Ensembl peptide - ENSP00000447400
Ensembl peptide - ENSP00000447888
Ensembl peptide - ENSP00000448036
Ensembl peptide - ENSP00000448269
Ensembl peptide - ENSP00000448612
Ensembl peptide - ENSP00000449000
Ensembl peptide - ENSP00000449421
Ensembl peptide - ENSP00000449904
Ensembl peptide - ENSP00000449907
Ensembl peptide - ENSP00000450050
Ensembl peptide - ENSP00000450158
Ensembl peptide - ENSP00000450159
Ensembl peptide - ENSP00000450265
Ensembl peptide - ENSP00000450305
Ensembl peptide - ENSP00000450417
NCBI entrez gene - 7009     See in Manteia.
OMIM - 600748
RefSeq - XM_005269126
RefSeq - NM_003217
RefSeq - NM_001098576
RefSeq Peptide - NP_001092046
RefSeq Peptide - NP_003208
swissprot - F8VPI1
swissprot - F8VQQ5
swissprot - F8VQW0
swissprot - P55061
swissprot - F8VR05
swissprot - F8VSI7
swissprot - F8VVJ4
swissprot - F8VX73
swissprot - F8VY06
swissprot - F8W086
swissprot - F8W1G3
swissprot - F8W1V3
swissprot - F8W201
swissprot - A0A0G2JKZ4
swissprot - A0A024R0Z5
Ensembl - ENSG00000139644
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tegtENSDARG00000077934Danio rerio
 Q9D2C7ENSMUSG00000023010Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006213  Bax inhibitor 1, conserved site
 IPR006214  Bax inhibitor 1-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006986 response to unfolded protein IEA
 biological_processGO:0010523 negative regulation of calcium ion transport into cytosol IDA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0051025 negative regulation of immunoglobulin secretion IEA
 biological_processGO:0060702 negative regulation of endoribonuclease activity IDA
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
 biological_processGO:1902065 response to L-glutamate IDA
 biological_processGO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IEA
 biological_processGO:1903298 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway IDA
 biological_processGO:1904721 obsolete negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response IDA
 biological_processGO:1990441 negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress IEA
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IDA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum TAS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0031966 mitochondrial membrane IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0060698 endoribonuclease inhibitor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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