ENSG00000139684


Homo sapiens

Features
Gene ID: ENSG00000139684
  
Biological name :ESD
  
Synonyms : ESD / esterase D / P10768
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q14.2
Gene start: 46771256
Gene end: 46797232
  
Corresponding Affymetrix probe sets: 209009_at (Human Genome U133 Plus 2.0 Array)   215096_s_at (Human Genome U133 Plus 2.0 Array)   228162_at (Human Genome U133 Plus 2.0 Array)   240808_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476193
Ensembl peptide - ENSP00000367969
Ensembl peptide - ENSP00000367992
Ensembl peptide - ENSP00000391350
NCBI entrez gene - 2098     See in Manteia.
OMIM - 133280
RefSeq - XM_017020414
RefSeq - NM_001984
RefSeq - XM_005266278
RefSeq - XM_011534954
RefSeq Peptide - NP_001975
swissprot - P10768
swissprot - U3KQT1
swissprot - X6RA14
swissprot - H7BZT7
swissprot - A0A140VJJ2
Ensembl - ENSG00000139684
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esdENSDARG00000019496Danio rerio
 ESDENSGALG00000016991Gallus gallus
 EsdENSMUSG00000021996Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000801  Putative esterase
 IPR014186  S-formylglutathione hydrolase
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0046294 formaldehyde catabolic process IEA
 biological_processGO:1901687 glutathione derivative biosynthetic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016788 hydrolase activity, acting on ester bonds IDA
 molecular_functionGO:0018738 S-formylglutathione hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0047374 methylumbelliferyl-acetate deacetylase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Glutathione conjugation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000139684 ESD / P10768 / esterase D  / complex






 

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