ENSG00000140284


Homo sapiens

Features
Gene ID: ENSG00000140284
  
Biological name :SLC27A2
  
Synonyms : O14975 / SLC27A2 / solute carrier family 27 member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q21.2
Gene start: 50182196
Gene end: 50236395
  
Corresponding Affymetrix probe sets: 205768_s_at (Human Genome U133 Plus 2.0 Array)   205769_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370289
Ensembl peptide - ENSP00000267842
Ensembl peptide - ENSP00000444549
NCBI entrez gene - 11001     See in Manteia.
OMIM - 603247
RefSeq - NM_003645
RefSeq - NM_001159629
RefSeq Peptide - NP_001153101
RefSeq Peptide - NP_003636
swissprot - O14975
swissprot - G3V1R7
Ensembl - ENSG00000140284
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O35488ENSMUSG00000027359Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9Y2P4 / SLC27A6 / solute carrier family 27 member 6ENSG0000011339651
Q9Y2P5 / SLC27A5 / solute carrier family 27 member 5ENSG0000008380745
Q5K4L6 / SLC27A3 / solute carrier family 27 member 3ENSG0000014355443
Q6PCB7 / SLC27A1 / solute carrier family 27 member 1ENSG0000013030439
Q6P1M0 / SLC27A4 / solute carrier family 27 member 4ENSG0000016711439


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain
 IPR030305  Fatty acid transport protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IEA
 biological_processGO:0001561 fatty acid alpha-oxidation TAS
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006635 fatty acid beta-oxidation IDA
 biological_processGO:0006699 bile acid biosynthetic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0042760 very long-chain fatty acid catabolic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0044539 long-chain fatty acid import IDA
 biological_processGO:0097089 methyl-branched fatty acid metabolic process IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane TAS
 cellular_componentGO:0005779 integral component of peroxisomal membrane IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004467 long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015245 fatty acid transmembrane transporter activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031957 very long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0050197 phytanate-CoA ligase activity TAS
 molecular_functionGO:0070251 pristanate-CoA ligase activity TAS
 molecular_functionGO:0102391 decanoate-CoA ligase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Alpha-oxidation of phytanate
Neutrophil degranulation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr