ENSG00000130304


Homo sapiens

Features
Gene ID: ENSG00000130304
  
Biological name :SLC27A1
  
Synonyms : Q6PCB7 / SLC27A1 / solute carrier family 27 member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 17468769
Gene end: 17506168
  
Corresponding Affymetrix probe sets: 226728_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472082
Ensembl peptide - ENSP00000470457
Ensembl peptide - ENSP00000472313
Ensembl peptide - ENSP00000252595
Ensembl peptide - ENSP00000469459
Ensembl peptide - ENSP00000469881
NCBI entrez gene - 376497     See in Manteia.
OMIM - 600691
RefSeq - XM_017026781
RefSeq - NM_198580
RefSeq - XM_011528000
RefSeq - XM_011528001
RefSeq - XM_011528002
RefSeq - XM_011528003
RefSeq Peptide - NP_940982
swissprot - M0QXY2
swissprot - M0QZC9
swissprot - B7Z225
swissprot - Q6PCB7
Ensembl - ENSG00000130304
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc27a1aENSDARG00000006240Danio rerio
 slc27a1bENSDARG00000104949Danio rerio
 Q60714ENSMUSG00000031808Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P1M0 / SLC27A4 / solute carrier family 27 member 4ENSG0000016711462
Q5K4L6 / SLC27A3 / solute carrier family 27 member 3ENSG0000014355438
Q9Y2P5 / SLC27A5 / solute carrier family 27 member 5ENSG0000008380737
O14975 / SLC27A2 / solute carrier family 27 member 2ENSG0000014028437
Q9Y2P4 / SLC27A6 / solute carrier family 27 member 6ENSG0000011339635


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR025110  AMP-binding enzyme, C-terminal domain
 IPR030308  Fatty acid transport protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001579 medium-chain fatty acid transport IEA
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process IMP
 biological_processGO:0006654 phosphatidic acid biosynthetic process IMP
 biological_processGO:0006655 phosphatidylglycerol biosynthetic process IMP
 biological_processGO:0006656 phosphatidylcholine biosynthetic process IMP
 biological_processGO:0006659 phosphatidylserine biosynthetic process IMP
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IMP
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009409 response to cold IEA
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0015909 long-chain fatty acid transport TAS
 biological_processGO:0019216 regulation of lipid metabolic process TAS
 biological_processGO:0031652 positive regulation of heat generation IEA
 biological_processGO:0032049 cardiolipin biosynthetic process IMP
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0033211 adiponectin-activated signaling pathway IEA
 biological_processGO:0071072 negative regulation of phospholipid biosynthetic process IMP
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004467 long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0015245 fatty acid transmembrane transporter activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0031957 very long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Transport of fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr