ENSMUSG00000031808


Mus musculus

Features
Gene ID: ENSMUSG00000031808
  
Biological name :Slc27a1
  
Synonyms : Q60714 / Slc27a1 / solute carrier family 27 (fatty acid transporter), member 1
  
Possible biological names infered from orthology : Q6PCB7 / solute carrier family 27 member 1
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: B3.3
Gene start: 71568882
Gene end: 71587302
  
Corresponding Affymetrix probe sets: 10572647 (MoGene1.0st)   1422811_at (Mouse Genome 430 2.0 Array)   1435658_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000148768
Ensembl peptide - ENSMUSP00000034267
Ensembl peptide - ENSMUSP00000148305
Ensembl peptide - ENSMUSP00000148616
NCBI entrez gene - 26457     See in Manteia.
MGI - MGI:1347098
RefSeq - XM_006509678
RefSeq - NM_011977
RefSeq - XM_006509671
RefSeq - XM_006509673
RefSeq - XM_006509674
RefSeq - XM_006509675
RefSeq - XM_006509676
RefSeq - XM_006509677
RefSeq Peptide - NP_001344110
RefSeq Peptide - NP_001344111
RefSeq Peptide - NP_036107
RefSeq Peptide - NP_001344109
swissprot - Q544D7
swissprot - A0A1D5RM39
swissprot - A0A1D5RLC0
swissprot - Q60714
Ensembl - ENSMUSG00000031808
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc27a1aENSDARG00000006240Danio rerio
 slc27a1bENSDARG00000104949Danio rerio
 Q6PCB7ENSG00000130304Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91VE0 / Slc27a4 / Long-chain fatty acid transport protein 4 / Q6P1M0* / solute carrier family 27 member 4*ENSMUSG0000005931660
Slc27a3 / solute carrier family 27 (fatty acid transporter), member 3 / Q5K4L6* / solute carrier family 27 member 3*ENSMUSG0000002793239
Q4LDG0 / Slc27a5 / Bile acyl-CoA synthetase / Q9Y2P5* / solute carrier family 27 member 5*ENSMUSG0000003038238
Slc27a6 / solute carrier family 27 member 6 / Q9Y2P4*ENSMUSG0000002460038
O35488 / Slc27a2 / Very long-chain acyl-CoA synthetase / O14975* / solute carrier family 27 member 2*ENSMUSG0000002735937


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site
 IPR030308  Fatty acid transport protein 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001579 medium-chain fatty acid transport IGI
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006646 phosphatidylethanolamine biosynthetic process IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process IEA
 biological_processGO:0006655 phosphatidylglycerol biosynthetic process ISO
 biological_processGO:0006656 phosphatidylcholine biosynthetic process IEA
 biological_processGO:0006659 phosphatidylserine biosynthetic process ISO
 biological_processGO:0006661 phosphatidylinositol biosynthetic process IEA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009409 response to cold IMP
 biological_processGO:0015908 fatty acid transport IEA
 biological_processGO:0015909 long-chain fatty acid transport IMP
 biological_processGO:0031652 positive regulation of heat generation IMP
 biological_processGO:0032049 cardiolipin biosynthetic process IEA
 biological_processGO:0032868 response to insulin IMP
 biological_processGO:0033211 adiponectin-activated signaling pathway IMP
 biological_processGO:0071072 negative regulation of phospholipid biosynthetic process ISO
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004467 long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0015245 fatty acid transmembrane transporter activity IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0031957 very long-chain fatty acid-CoA ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Transport of fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000187 abnormal triglyceride level "anomalous concentration of this molecule, glycerol esterified at each of its three hydroxyl groups by a fatty acid; triglyceride is an important molecule for storage of fatty acids in adipose tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0001547 abnormal lipid level "anomalous concentrations of fat-soluble substances (molecules composed of carbon and hydrogen and are characteristically insoluble in water) in the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0002078 abnormal glucose homeostasis "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0004130 abnormal muscle cell glucose uptake "anomaly in the ability of muscle cells to take in glucose" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

 MP:0005280 abnormal fatty acid level "anomalous concentration of organic, monobasic acids derived from hydrocarbons and which are complexed with serum albumin for transport; they are saturated and unsaturated" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Psme3tm1Tchi/Psme3tm1Tchi
Genetic Background: involves: C57BL/6J * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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