ENSG00000140323


Homo sapiens

Features
Gene ID: ENSG00000140323
  
Biological name :DISP2
  
Synonyms : A7MBM2 / DISP2 / dispatched RND transporter family member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q15.1
Gene start: 40358235
Gene end: 40378639
  
Corresponding Affymetrix probe sets: 1562834_at (Human Genome U133 Plus 2.0 Array)   229579_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000267889
NCBI entrez gene - 85455     See in Manteia.
OMIM - 607503
RefSeq - XM_017022687
RefSeq - NM_033510
RefSeq - XM_011522125
RefSeq Peptide - NP_277045
swissprot - A7MBM2
Ensembl - ENSG00000140323
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 disp2ENSDARG00000042846Danio rerio
 DISP2ENSGALG00000031266Gallus gallus
 2 ENSMUSG00000040035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DISP1 / Q96F81 / dispatched RND transporter family member 1ENSG0000015430937
DISP3 / Q9P2K9 / dispatched RND transporter family member 3ENSG0000020462417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000731  Sterol-sensing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007224 smoothened signaling pathway NAS
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Release of Hh-Np from the secreting cell


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175356 Q9NQ36 / SCUBE2 / signal peptide, CUB domain and EGF like domain containing 2  / reaction
 ENSG00000164690 SHH / Q15465 / sonic hedgehog  / reaction / complex






 

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