ENSG00000140400


Homo sapiens

Features
Gene ID: ENSG00000140400
  
Biological name :MAN2C1
  
Synonyms : MAN2C1 / mannosidase alpha class 2C member 1 / Q9NTJ4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q24.2
Gene start: 75355207
Gene end: 75368630
  
Corresponding Affymetrix probe sets: 203668_at (Human Genome U133 Plus 2.0 Array)   238230_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456914
Ensembl peptide - ENSP00000456667
Ensembl peptide - ENSP00000457788
Ensembl peptide - ENSP00000479988
Ensembl peptide - ENSP00000457833
Ensembl peptide - ENSP00000267978
Ensembl peptide - ENSP00000390738
Ensembl peptide - ENSP00000454406
Ensembl peptide - ENSP00000454589
Ensembl peptide - ENSP00000455788
Ensembl peptide - ENSP00000455803
Ensembl peptide - ENSP00000455998
Ensembl peptide - ENSP00000456257
Ensembl peptide - ENSP00000456419
NCBI entrez gene - 4123     See in Manteia.
OMIM - 154580
RefSeq - XM_017022188
RefSeq - NM_001256494
RefSeq - NM_001256495
RefSeq - NM_001256496
RefSeq - NM_006715
RefSeq - XM_005254384
RefSeq - XM_017022186
RefSeq - XM_017022187
RefSeq Peptide - NP_001243424
RefSeq Peptide - NP_001243425
RefSeq Peptide - NP_006706
RefSeq Peptide - NP_001243423
swissprot - B4DH23
swissprot - A0A140VJN9
swissprot - H3BMJ3
swissprot - H3BQH9
swissprot - H3BQJ2
swissprot - H3BRI3
swissprot - H3BSE5
swissprot - H3BRV3
swissprot - H3BUW3
swissprot - Q9NTJ4
swissprot - A0A0C4DGU9
Ensembl - ENSG00000140400
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 man2c1ENSDARG00000079835Danio rerio
 MAN2C1ENSGALG00000001615Gallus gallus
 Man2c1ENSMUSG00000032295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily
 IPR037094  Glycoside hydrolase family 38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IEA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009313 oligosaccharide catabolic process TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005773 vacuole IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Lysosomal oligosaccharide catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr