ENSG00000140450


Homo sapiens

Features
Gene ID: ENSG00000140450
  
Biological name :ARRDC4
  
Synonyms : ARRDC4 / arrestin domain containing 4 / Q8NCT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q26.2
Gene start: 97960698
Gene end: 97973838
  
Corresponding Affymetrix probe sets: 225283_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000268042
NCBI entrez gene - 91947     See in Manteia.
RefSeq - NM_183376
RefSeq Peptide - NP_899232
swissprot - A0A024RC80
swissprot - Q8NCT1
Ensembl - ENSG00000140450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ARRDC4ENSGALG00000007012Gallus gallus
 Arrdc4ENSMUSG00000042659Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARRDC3 / Q96B67 / arrestin domain containing 3ENSG0000011336950
ARRDC2 / Q8TBH0 / arrestin domain containing 2ENSG0000010564344
TXNIP / Q9H3M7 / thioredoxin interacting proteinENSG0000026597241
ARRDC1 / Q8N5I2 / arrestin domain containing 1ENSG0000019707024


Protein motifs (from Interpro)
Interpro ID Name
 IPR011021  Arrestin-like, N-terminal
 IPR011022  Arrestin C-terminal-like domain
 IPR014756  Immunoglobulin E-set


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IPI
 biological_processGO:0140112 extracellular vesicle biogenesis ISS
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:1903561 extracellular vesicle ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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