ENSG00000141552


Homo sapiens

Features
Gene ID: ENSG00000141552
  
Biological name :ANAPC11
  
Synonyms : ANAPC11 / anaphase promoting complex subunit 11 / Q9NYG5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.3
Gene start: 81890790
Gene end: 81900991
  
Corresponding Affymetrix probe sets: 224010_at (Human Genome U133 Plus 2.0 Array)   226414_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464519
Ensembl peptide - ENSP00000464403
Ensembl peptide - ENSP00000464615
Ensembl peptide - ENSP00000484031
Ensembl peptide - ENSP00000339695
Ensembl peptide - ENSP00000349957
Ensembl peptide - ENSP00000376181
Ensembl peptide - ENSP00000458143
Ensembl peptide - ENSP00000458265
Ensembl peptide - ENSP00000458515
Ensembl peptide - ENSP00000459200
Ensembl peptide - ENSP00000460064
Ensembl peptide - ENSP00000460678
Ensembl peptide - ENSP00000461648
Ensembl peptide - ENSP00000462250
Ensembl peptide - ENSP00000462527
Ensembl peptide - ENSP00000462691
Ensembl peptide - ENSP00000463357
Ensembl peptide - ENSP00000463567
Ensembl peptide - ENSP00000463598
Ensembl peptide - ENSP00000463640
Ensembl peptide - ENSP00000463889
NCBI entrez gene - 51529     See in Manteia.
OMIM - 614534
RefSeq - NM_001289415
RefSeq - NM_001002244
RefSeq - NM_001002245
RefSeq - NM_001002246
RefSeq - NM_001002247
RefSeq - NM_001002248
RefSeq - NM_001002249
RefSeq - NM_001289414
RefSeq - NM_001289416
RefSeq - NM_001289417
RefSeq - NM_001289418
RefSeq - NM_001289419
RefSeq - NM_001289420
RefSeq - NM_016476
RefSeq Peptide - NP_001276347
RefSeq Peptide - NP_001276348
RefSeq Peptide - NP_001276349
RefSeq Peptide - NP_057560
RefSeq Peptide - NP_001002248
RefSeq Peptide - NP_001002249
RefSeq Peptide - NP_001276343
RefSeq Peptide - NP_001276344
RefSeq Peptide - NP_001276345
RefSeq Peptide - NP_001276346
RefSeq Peptide - NP_001002244
RefSeq Peptide - NP_001002245
RefSeq Peptide - NP_001002246
RefSeq Peptide - NP_001002247
swissprot - Q9NYG5
swissprot - J3QS46
swissprot - A0A024R8S1
swissprot - A0A087X1B5
swissprot - J3KSK3
swissprot - J3QL35
Ensembl - ENSG00000141552
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc11ENSDARG00000102531Danio rerio
 ENSGALG00000023308Gallus gallus
 Q9CPX9ENSMUSG00000025135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR024991  Anaphase-promoting complex subunit 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0031145 anaphase-promoting complex-dependent catabolic process TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0045842 positive regulation of mitotic metaphase/anaphase transition IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051436 obsolete negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
 biological_processGO:0051437 obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition TAS
 biological_processGO:0051439 obsolete regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS
 biological_processGO:0070979 protein K11-linked ubiquitination IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005680 anaphase-promoting complex IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0034450 ubiquitin-ubiquitin ligase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA
 molecular_functionGO:0097602 cullin family protein binding IDA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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