ENSMUSG00000025135


Mus musculus

Features
Gene ID: ENSMUSG00000025135
  
Biological name :Anapc11
  
Synonyms : Anapc11 / Anaphase-promoting complex subunit 11 / Q9CPX9
  
Possible biological names infered from orthology : Q9NYG5
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: E2
Gene start: 120598421
Gene end: 120608198
  
Corresponding Affymetrix probe sets: 10383423 (MoGene1.0st)   1417326_a_at (Mouse Genome 430 2.0 Array)   1447897_x_at (Mouse Genome 430 2.0 Array)   1459212_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026128
Ensembl peptide - ENSMUSP00000097714
NCBI entrez gene - 66156     See in Manteia.
MGI - MGI:1913406
RefSeq - NM_001038230
RefSeq - NM_025389
RefSeq Peptide - NP_001033319
RefSeq Peptide - NP_079665
swissprot - Q9CPX9
Ensembl - ENSMUSG00000025135
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anapc11ENSDARG00000102531Danio rerio
 ENSGALG00000023308Gallus gallus
 Q9NYG5ENSG00000141552Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR024991  Anaphase-promoting complex subunit 11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0045842 positive regulation of mitotic metaphase/anaphase transition IBA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070979 protein K11-linked ubiquitination ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005680 anaphase-promoting complex IBA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0034450 ubiquitin-ubiquitin ligase activity ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO
 molecular_functionGO:0097602 cullin family protein binding ISO


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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