ENSG00000141577


Homo sapiens

Features
Gene ID: ENSG00000141577
  
Biological name :CEP131
  
Synonyms : centrosomal protein 131 / CEP131 / Q9UPN4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.3
Gene start: 81189593
Gene end: 81222999
  
Corresponding Affymetrix probe sets: 214742_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461374
Ensembl peptide - ENSP00000460006
Ensembl peptide - ENSP00000460098
Ensembl peptide - ENSP00000269392
Ensembl peptide - ENSP00000363914
Ensembl peptide - ENSP00000393583
Ensembl peptide - ENSP00000459733
NCBI entrez gene - 22994     See in Manteia.
OMIM - 613479
RefSeq - XM_017024369
RefSeq - NM_001319229
RefSeq - NM_014984
RefSeq - XM_011524547
RefSeq - XM_011524548
RefSeq - XM_011524550
RefSeq - XM_011524551
RefSeq - XM_011524552
RefSeq - XM_011524553
RefSeq - XM_011524555
RefSeq - NM_001009811
RefSeq - NM_001319228
RefSeq Peptide - NP_001306157
RefSeq Peptide - NP_001306158
RefSeq Peptide - NP_055799
RefSeq Peptide - NP_001009811
swissprot - I3L2X7
swissprot - Q9UPN4
swissprot - I3L316
swissprot - I3L4M5
swissprot - I3L2J8
Ensembl - ENSG00000141577
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cep131ENSDARG00000088984Danio rerio
 CEP131ENSGALG00000006895Gallus gallus
 Cep131ENSMUSG00000039781Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR030465  Centrosomal protein of 131kDa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035735 intraciliary transport involved in cilium assembly IEA
 biological_processGO:0071539 protein localization to centrosome IMP
 biological_processGO:0090316 positive regulation of intracellular protein transport IMP
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034451 centriolar satellite IDA
 cellular_componentGO:0035869 ciliary transition zone IDA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0045171 intercellular bridge IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044877 protein-containing complex binding IDA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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